A team of scientists from the Massachusetts Institute of Technology has created microparticles that can be used to develop self-sustaining vaccines. The findings of the work are published in the journal Science Advances.
Specialists presented microparticles made of biocompatible PLGA polymer (used in implants, prostheses, etc.), into which a vaccine preparation can be sealed. Once injected, the particles will gradually release the desired substance. If doctors need part of the vaccine to enter the body six months after administration, more resistant polymers will be used, and if after three months, more rapidly decomposing ones (similar to some types of sutures).
The technology can be applied to all types of vaccines, such as recombinant protein vaccines, DNA or RNA based vaccines. In addition, the scientists noted that their development would be useful for the delivery of other types of drugs (cancer drugs or hormone therapy).